Nucleic Acid Production Engineer
かくさんせいさんぎじゅつしゃ
Industry & Occupation
Classification
- Major : Research and Technical Occupations
- Middle : Manufacturing Engineers
- Minor : Chemical Product Manufacturing Engineers
Summary
Technical position that designs, operates, and manages manufacturing processes for nucleic acid (DNA/RNA) molecules from research and development to mass production.
Description
Nucleic acid production engineers handle a series of manufacturing processes to mass-produce nucleic acid molecules, such as mRNA vaccines and RNA/DNA agents for gene therapy, with high quality and purity. In upstream processes, they optimize chemical synthesis and transcription reactions using enzymatic reactions. In downstream processes, they perform purification using chromatography and ultracentrifugation. They also conduct work in cleanrooms based on GMP standards, equipment validation, and quality testing (HPLC, mass spectrometry, electrophoresis, etc.). They are responsible for scaling up manufacturing, troubleshooting manufacturing processes, developing and improving production plans in collaboration with other departments, and enhancing the quality and efficiency of the overall process.
Future Outlook
With the expansion of the biopharmaceutical market, demand for nucleic acid manufacturing engineers is increasing. Personnel skilled in automation and AI-driven process optimization technologies are sought.
Personality Traits
Cautious / Eager to Learn / Good Team Player / Strong Sense of Responsibility
Work Style
Career Path
Operator → Chief Engineer → Process Development Engineer → Quality Assurance/Quality Control Specialist → Manufacturing Department Manager
Required Skills
Aseptic Technique / Chromatography / Design of Experiments / GMP Fundamentals / Mass Spectrometry Operation
Recommended Skills
Bioinformatics Basics / English Paper Reading / Scale-up Technology / Statistical Analysis
Aptitudes (Strengths Preferred)
| Item | Description |
|---|---|
| Attention to Detail & Accuracy | Because precise operations are required. |
| Learning Agility & Knowledge Acquisition | Because technological innovations are rapid and the introduction of new technologies is required. |
| Problem Solving | Because identifying the causes of problems in manufacturing processes is necessary. |
Related Qualifications
- Biotechnologist Certification Exam
- GMP-related Qualifications
- Quality Management Certification
Aliases
- DNA Production Engineer
- Nucleic Acid Manufacturing Engineer
- RNA Production Engineer
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